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Gentamicin

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CAS: Gentamicin 
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Updated on: 2012-04-13
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Description

[Category] antibiotics \ aminoglycoside
[Alias​​] gentamicin sulfate, neomycin Chint, children Liberty, gentamicin, gentamicin, Rui Beike (sustained-release tablets)

Foreign Name] Gentamicin, Gentamicin Sulfate, Cidomycin, Garamycin, Gentalin

Indications
Mainly used for E. coli, Shigella, g enzyme White Klebsiella pneumoniae, Proteus, Pseudomonas aeruginosa and other gram-negative bacteria cause a system or local infection.

Consumption usage
1 IM: 1 per kilogram body weight 1.5mg (or each 80mg), every 8 hours. For Gram-negative bacteria Pseudomonas aeruginosa caused by severe infection or systemic infection, 1 volume per kilogram body weight can be used to 5mg. Intravenous administration of 1 could be the amount (80mg), diluted with 100ml of liquid, in about 30 minutes infusion, 1 dose 3 times. Newborns per kilogram body weight on the 1st 2 ~ 4mg, 2 times to give. 2 Oral: daily 240 ~ 640mg, 1 child per kilogram of body weight as the amount of 15mg, four times a service for the intestinal infection or preoperative preparation.
Renal dysfunction, dose, calculated according to Ccr
Ccr (ml / min) Adult usual dose (%) Ccr (ml / min) Adult usual dose (%)
> 10010030-3535
70-100 8525-3030
55-706520-2525
45-555515-2020
40-455010-1515
35-4040 <10 10


[Notes]
1 for renal dysfunction or long-term medication should be drug monitoring. 2 1, the amount of the product should be administered 2 to 3 times in order to maintain effective blood concentration, and reduce toxicity. Do not focus on the amount of 1 1 to give. 3 toxicity and kanamycin approximate, due to small doses, so the toxicity of a little light. However, if treatment with excessive or prolonged, can still occur ear, kidney damage, should be noted. 4 of streptococcal infection is invalid. Caused by streptococcal upper respiratory tract infection should not be used. 5 to inhibit respiration, not intravenous injection.

[Specifications] Injection: Each 40mg (1ml), 80mg (2ml). Tablet: Each tablet 40mg. Granules: 5g / bag
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