Rupintrivir is a potent and selective irreversible human rhinovirus (HRV) 3C protease inhibitor (EC50 = 5 nM). It has been demonstrated to have in vitro activity against all HRVs tested, consistent with its interaction with a strictly conserved subset of amino acids in the 3C protease. It blocks processing of viral proteins, thus blocking viral replication.
https://www.bocsci.com/rupintrivir-cas-223537-30-2-item-14601.html