GHRP-2 CAS: 158861-67-7 as a Growth Hormone Secretagogue

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Quick Details:

Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2

Molecular formula: C45H55N9O6

Molar Mass: 817.9

CAS number: 158861-67-7

PubChem: CID 6918245 

Synonyms: Growth Hormone Releasing Peptide-2; GHRP2; GHRP 2

Growth Hormone Releasing Peptide 2

GHRP-2 and GRF Analogue Interactions (CJC-1295 / Sermorelin)

It is important to know that GHRP-2 does not relate to any Growth Hormone Releasing Hormones (GHRH) peptides such as Sermorelin and CJC-1295 because it acts on different receptors. However, greater results occurred when administered in conjunction with a Growth Hormone Releasing Hormone (GHRH) such as Modified GRF 1-29 or CJC-1295 DAC. Naturally, these GHRP-2 peptide receptors interact with a hormone called ghrelin. Growth hormone releasing peptide 2 is a commercially synthesized, non-natural super-analog of GHRP-6 which is capable of potent stimulatory effect on growth hormone (GH) secretion with slight stimulator effect in PRL, ACTH and levels of cortisol (Arvat et al. 1997). It is also a synthetic agonist of ghrelin that is binding with the growth hormone (GH) secretagogue receptor. GHRP-2 has been shown to affect and induce growth hormone secretion. The response of natural physiologic system includes increase in levels of calcium ion influx alongside with increased release of growth hormones in response to this peptide (Wu et al. 1994)